Table 3.
Comparison of the thyroid function and quality of life in patients with GD between low and high LPS subgroup.
| Variables | Low level LPS | High level LPS | p |
|---|---|---|---|
| Sample size | 45 | 46 | |
| LPS | 110.2 (93.0-128.1) | 204.6 (177.2-284.2) | <0.001 |
| Thyroid function | |||
| TGAb (IU/ml) | 337.4 (21.9-582.6) | 162.0 (14.7-677.9) | 0.275 |
| TPOAb (IU/ml) | 193.3 (76.4-294.2) | 274.1 (50.5-474.0) | 0.959 |
| TRAb (IU/L) | 7.2 ± 10.0 | 14.4 ± 12.1 | 0.003 |
| FT3 (pmol/L) | 7.1 ± 5.9 | 12.6 ± 5.8 | <0.001 |
| FT4 (pmol/L) | 15.4 (13.2-24.3) | 47.5 (28.1-62.9) | <0.001 |
| TSH (mIU/L) | 0.99 (0.014-2.541) | 0.005 (0.003-0.008) | <0.001 |
| Quality of life | |||
| Hyperthyroid symptoms | 12.5 (0-25) | 39.5 (24.4-64.0) | <0.001 |
| Hypothyroid symptoms | 12.5 (6.2-18.7) | 16.6 (6.2-25) | 0.135 |
| Goiter symptoms | 0 (0-8.3) | 8.3 (0-10.4) | 0.289 |
| Eye symptoms | 8.3 (0-16.6) | 25 (8.3-41.6) | 0.004 |
| Tiredness | 33.3 (16.6-41.6) | 41.6 (25-50) | 0.142 |
| Cognitive complaints | 8.3 (0-25) | 16.6 (8.3-25) | 0.426 |
| Anxiety | 16.7 (0-25) | 16.6 (6.2-25) | 0.430 |
| Depressivity | 16.6 (8.3-33.3) | 16.6 (8.3-33.3) | 0.505 |
| Emotional susceptibility | 25 (16.6-33.3) | 29.1 (14.5-52) | 0.289 |
| Impaired social life | 8.3 (0-16.6) | 8.3 (0-25) | 0.829 |
| Impaired daily life | 0 | 8.3 (0-10.4) | 0.003 |
| Cosmetic complaints | 8.3 (0-16.6) | 8.3 (0-25) | 0.658 |
Significant p values are bolded.