Table 2.

Summary of recent meta-analysis of neuraxial anaesthesia and cancer recurrence.

Author	Year	Regional anaesthesia	Total Number of studies analysed	Findings
Lee et al. (65)	2020	Epidural and paravertebral anaesthesia	6 (3,139 patients in the regional anaesthesia group)	Adjunctive use of epidural or paravertebral anaesthesia with general anaesthesia did not reduce the rate of cancer recurrence following cancer surgery.
Weng et al. (61)	2016	Epidural and Spinal anaesthesia	20 (15,160 patients in regional anaesthesia group)	Neuraxial anaesthesia appears to improve overall survival, specifically in colorectal cancer surgery and may be associated with reduced risk of cancer recurrence.
Sun et al. (62)	2015	Epidural and Spinal anaesthesia	20 (16,618 patients in regional anaesthesia group)	Perioperative neuraxial anaesthesia may improve overall survival after cancer surgery but it had no positive influence in the reduction of cancer recurrence.
Lee et al. (64)	2015	Epidural and Spinal anaesthesia	10 (7,504 patients in regional anaesthesia group)	Neuraxial anaesthesia during prostate cancer surgery appears to improve overall survival but was not associated with longer recurrence-free-survival.
Pej et al. (63)	2014	Epidural anaesthesia	10 (3,254 patients in regional anaesthesia group)	Perioperative epidural anaesthesia did not influence postoperative cancer recurrence and metastasis rate. However, epidural anaesthesia may be associated with improvement in prognosis of prostate cancer surgery with a follow-up of less than or equal to two years.