Table 2.
ROS production and SOD activity following LPS-induced acute lung injury Oxidative stress measurements.
Parameters | Control | LPS | LPS + Scutellarin | LPS + Scutellrin + SP600125 |
---|---|---|---|---|
ROS | 109.11 ± 1.11 | 152.3 ± 4.11* | 129.12 ± 2.95* | 149.99 ± 4.21 |
SOD | 60.77 ± 1.88 | 51.25 ± 1.44* | 66.23 ± 2.01* | 52.78 ± 1.85 |
ROS production and SOD activity following experimental acute lung injury caused by LPS plus treatment with SP600125 or scutellarin. LPS treatment robustly augmented the levels of ROS generation while decreasing SOD activity. However, after scutellarin significantly downregulate the levels of ROS and augmented SOD activity (*P < 0.05, 2)