Table 5.

Allele frequency distribution of OCT gene polymorphisms.

SNPs	Population	Case/control	Alleles in cases		Alleles in controls		P-value	Reference
			G	A	G	A
OCT1 rs628031	China	153/124	0.72	0.28	0.74	0.26	*	Zhou et al., 2015
	Indonesia	86/NA	0.61	0.39	NA	NA	NS	Vitarani et al., 2017
	Saudi Arabia	201/89	0.69	0.31	0.71	0.29	NS	Altall et al., 2019
	Latvia	53/193	0.27	0.73	0.24	0.76	*	Tarasova et al., 2012
	Iran	63/77	0.32	0.68	0.33	0.66	NS	Shokri et al., 2016
	Present study	132/133	0.27	0.73	0.22	0.78	NS
			C	T	C	T
OCT2 rs145450955	Iran	40/NA	0.8	0.2	NA	NA	*	Kashi et al., 2015
	Present study	132/133	0.6	0.4	0.67	0.33	NS
			G	A	G	A
OCT3 rs3088442	Iran	150/152	NR	NR	NR	NR	**	Mahrooz et al., 2017
	Pakistan	600/300	0.67	0.33	0.54	0.46	**	Moeez et al., 2019
	Present study	132/133	0.69	0.31	0.31	0.29	NS
			G	A	G	A
OCT3 rs2292334	Iran	150/152	0.65	0.35	0.75	0.25	*	Mahrooz et al., 2017
	Present study	132/133	0.69	0.31	0.77	0.23	NS

NA, not available; NR, not reported; NS, not significant; *(p < 0.05); **(P < 0.001).