TABLE 5.
Quantified changes in solute concentrations between different degeneration grades
| Degeneration progression | Glucose | Lactate | Oxygen |
|---|---|---|---|
| Grade 2—Grade 3 | −2.79% | 4.84% | −0.91% |
| Grade 3—Grade 4 | −2.54% | 7.59% | −1.53% |
| Grade 4—Grade 5 | 1.55% | −3.81% | 1.10% |
| Degeneration progression | Minimum glucose | Maximum lactate | Minimum oxygen |
|---|---|---|---|
| Grade 2—Grade 3 | −4.80% | 4.79% | −2.17% |
| Grade 3—Grade 4 | −31.1% | 28.2% | −13.9% |
| Grade 4—Grade 5 | 16.5% | −8.00% | 6.39% |
Note: COMSOL Multiphysics 5.4 automatically identified minimum and maximum solute values in the IVD. However, all points fell within the inner AF (except for the following patients: #13, #15, and #18 in grade 4; and patient #20 in grade 5). (n = 10 for grades 2, 3, 4 and n = 7 for grade 5).