Baseline 18F-FDHT uptake and qualitative AR status. (A) For 9 participants with archival tissue, median baseline 18F-FDHT SUVmax was 4.1 (range, 1.4–5.9) for 7 participants with AR+ tumors and 2.3 (range, 1.5–3.2) for 2 with AR− tumors (P = 0.22). Individual dots on box plot represent individual-participant data. (B, top row: axial CT; middle row: axial PET; bottom row: axial fused PET/CT) Participant 6, with AR+ tumor and 18F-FDHT uptake in right femur metastasis (arrows, SUVmax of 4.9). (C, top row: axial CT; middle row: axial PET; bottom row: axial fused PET/CT) Participant 8, with AR− tumor and no 18F-FDHT uptake in prevascular lymph node (arrows, SUVmax of 1.5).