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SNX5 inhibits ccRCC cell migration and invasion
(A) Transwell analysis showed that the overexpression of SNX5 inhibited ccRCC cell migration and invasion. (B) Transwell analysis showed that knockdown of SNX5 promoted ccRCC cell migration and invasion. (C) The expression of MMP2, MMP7, and MMP9 was detected by western blot in SNX5-overexpressing cells and (D) SNX5 knockdown cells. (E) H&E staining showing lung metastasis in mice injected via tail vein. ∗p < 0.05; ∗∗p < 0.01.
