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. 2021 Aug 23;70(1):29–35. doi: 10.1136/jim-2020-001715

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© American Federation for Medical Research 2022. Re-use permitted under CC BY-NC. No commercial re-use. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, an indication of whether changes were made, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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H&E staining of renal slices of sham-operated, saline and ischemia/reperfusion (I/R)+butyrate-treated rats 24 hours after renal I/R (×50). Massive hemorrhages and necrosis with neutrophil infiltration were observed in the kidney of saline-treated rats, meanwhile, butyrate-treated rats demonstrated attenuated pathological damages induced by I/R. Limited areas and severity of renal tubular epithelial cell swelling and necrosis were demonstrated by the H&E staining, indicating less neutrophil infiltration.