Scheme 2. Preparation of Nanocatalyst 2 and Its Catalytic Evaluation.
(a) Fe3O4@SiO2, toluene, 105 °C, 12 h; (b) ephedrine, DIPEA, toluene, 105 °C, 48 h, loading: 0.22 mmol/g; (c) toluene, 6 mol % of 2, 0 °C, 6 h, 25% yield, 0% ee.
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