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. 2021 Dec 15;6(51):35559–35571. doi: 10.1021/acsomega.1c05119

Figure 6.

Figure 6

AFM topographical images of HSA in the absence and presence of Cu(II) ions. (a,b) Free HSA and the respective height profile at physiological pH. (c,d) Formation of oligomers after introducing 3.75 μM Cu(II) and the corresponding height profiles. (e–i) Amorphous aggregate formation after an incubation period of 10 days with the introduction of 7.50, 11.30, 17.50, 32.50, and 37.50 μM Cu(II) ions.