Fig. 2.
RF and reactive gliosis proteins are among the most changed in the quantified proteome of GFAPTg;Gfap+/R236Hmice versus wild type. Heat map of proteins previously documented in AxD to have altered abundance, as well as three reactive gliosis proteins (Fabp7, Aldh1l1, Ndrg2) that have not previously been linked to AxD phenotype. Data shown are the individual mouse Log2 normalized protein fold-change values in every sample. Proteins without detectable amounts in a particular sample were assigned a Log2 normalized fold-change value of −1 (dark blue in the heat map).