Table 1.
Differentially regulated protein signaling pathways in GFAPTg;Gfap+/R236H mice
Upregulated pathways | Increased proteins in the pathway | p-value |
---|---|---|
Glutathione metabolism | Gsta3, Gstm1, Gclc, Gpx4, Pgd, Gclm, Gss, Gsto1, Gpx3, Gpx1, Idh2 | 1.47E-04 |
PPAR signaling | Ilk, Fabp7, Sorbs1, Apoa1, Acadl, Acsl3, Acox3, Pck2, Acox1 | 2.75E-03 |
Pathways assigned a p-value ≤ 0.01 by the DAVID analysis tool are displayed. Protein abbreviations shown correspond to Swiss-Prot genes. No significant pathways using the list of downregulated proteins were observed.