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. 2021 Dec 16;9:773050. doi: 10.3389/fcell.2021.773050

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Copyright © 2021 Shi, Han, Yao, Liu, Jiang and Yan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of miRNA profiling of EPCs derived from the bone marrow. (A) The box plot is depicted to show the distribution of miRNA expression pattern across different samples. The boxes with a central line and two tails represent the median of the data and the upper and lower quartiles, respectively. (B) The volcano plot shows the differentially expressed miRNAs between EPCs derived from the bone marrow with or without high-glucose treatment. (C) Heatmaps generated from hierarchical cluster analysis display 20 differentially expressed miRNAs between EPCs derived from the bone marrow with or without high-glucose treatment. Yellow color and blue color indicate the up-regulated and down-regulated miRNAs, respectively.