Figure 1:

Plasma Budesonide levels across time. (A) Plasma levels of animals receiving surfactant and budesonide prior to ventilation (protective VT) were proportionate to the dose given at every time point and decreased across time. A significant dose was present in the plasma by 15 minutes after intra-tracheal dose. (B) Animals receiving 15 minutes of mechanical ventilation prior to surfactant and budesonide (Injury VT) had a similar pattern of budesonide in the plasma. Mean ± SEM. * p < 0.05 vs 0.1 and 0.04 mg/kg; # p < 0.05 vs 0.04 mg/kg