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. 2021 Jul 26;6(4):658–667. doi: 10.1136/svn-2021-001032

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Neutrophil extracellular traps (NETs) in stroke emboli. Serial sections of thrombi retrieved from ischaemic stroke patients were stained with antibody against citrullinated histone H3 (H3Cit) to reveal the presence of NETs. (A–C) Representative microphotographs of three different patients’ thrombi stained for H3Cit (red), showing NETs is expressed along the surface of thrombus (A), at junctions between RBC-rich and platelet rich-regions (B and C). (Immunohistochemistry, original magnification ×3.7 (A), ×4.9 (B and C)).