Table 3.

Sensitivity analysis for different methods of adjustment

Outcome	Adjusted OR or mean difference (95% CI)*	P value	Adjusted OR or mean difference (95% CI)†	P value
mRS scores 0 to 1 at 90 days	1.19 (1.00 to 1.42)	0.047	1.15 (0.98 to 1.35)	0.078
mRS scores 0 to 2 at 90 days	1.27 (1.04 to 1.56)	0.021	1.22 (1.01 to 1.46)	0.036
mRS distribution at 90 days		0.060		0.140
ΔNIHSS score to 24 hours‡	0.24 (−0.07 to 0.55)	0.125	0.23 (−0.10 to 0.57)	0.173
ΔNIHSS score to 14 days‡	0.28 (−0.09 to 0.65)	0.133	0.28 (−0.14 to 0.70)	0.194
sICH at 36 hours	0.72 (0.36 to 1.43)	0.349	0.69 (0.35 to 1.35)	0.281
Other bleeding events	1.43 (0.64 to 3.19)	0.384	1.48 (0.66 to 3.29)	0.341
Recurrent stroke at 90 days	0.57 (0.34 to 0.95)	0.030	0.57 (0.34 to 0.94)	0.028
All-cause mortality at 90 days	0.74 (0.49 to 1.11)	0.148	0.76 (0.52 to 1.12)	0.164

*Adjustment with all baseline variables in the model.

†Propensity scores used to adjust all baseline variables in the model.

‡From baseline.

mRS, modified Rankin scale; NIHSS, National Institutes of Health Stroke Scale; rt-PA, recombinant tissue plasminogen activator; sICH, symptomatic intracerebral haemorrhage; UK, urokinase.