. Author manuscript; available in PMC: 2021 Dec 30.

Published in final edited form as: Am J Transplant. 2020 Mar 12;20(8):2101–2112. doi: 10.1111/ajt.15825

TABLE 3.

Likelihood of different transplant modalities among highly sensitized candidates by era and cPRA category

	aSHR

	Era 2 vs Era 1¹	Era 3 vs Era 1¹	Era 3 vs Era 2¹
Overall
DDKT	0.97^1.041.12	1.74 ^1.85 1.97	1.67 ^1.77 1.89
LDKT	0.86^1.001.16	0.99^1.131.30	0.99^1.131.30
Non-KPD	0.65 ^0.78 0.94	0.69 ^0.82 0.97	0.87^1.041.25
KPD	1.31 ^1.73 2.29	1.70 ^2.20 2.84	1.02 ^1.27 1.57
cPRA
80%-89%
DDKT	0.94^1.031.15	0.76 ^0.84 0.92	0.73 ^0.81 0.89
LDKT	0.71^0.891.11	1.05 ^1.27 1.53	1.16 ^1.43 1.76
Non-KPD	0.54 ^0.70 0.92	0.83^1.041.31	1.14 ^1.49 1.93
KPD	1.02 ^1.53 2.29	1.41 ^2.03 2.91	0.95^1.331.85
90%-97%
DDKT	0.95^1.071.22	1.75 ^1.95 2.17	1.64 ^1.82 2.02
LDKT	0.92^1.181.52	0.98^1.241.58	0.84^1.051.32
Non-KPD	0.67^0.921.25	0.58^0.781.07	0.62^0.851.17
KPD	1.25 ^1.98 3.13	1.71 ^2.62 4.00	0.94^1.321.86
98%-99.9%
DDKT	0.96^1.201.49	5.57 ^6.62 7.85	4.71 ^5.52 6.48
LDKT	0.80^1.151.65	0.63^0.911.31	0.56^0.791.13
Non-KPD	0.59^0.901.39	0.37 ^0.58 0.92	0.40^0.641.03
KPD	1.05 ^2.21 4.66	1.14 ^2.32 4.73	0.61^1.051.81
99.9%+
DDKT	0.38^0.701.31	4.23 ^6.49 9.96	5.73 ^9.24 14.90
LDKT	0.47^1.313.67	0.35^0.952.59	0.30^0.731.73
Non-KPD	0.36^1.284.54	0.21^0.772.79	0.19^0.601.85
KPD	0.24^1.377.99	0.27^1.336.68	0.24^0.973.93

Note: Bold indicates P < .05.

Abbreviations: aSHR, adjusted subhazard ratio; cPRA, calculated panel reactive antibody, DDKT, deceased donor kidney transplantation; KPD, kidney-paired donation; LDKT, living donor kidney transplantation.

Reference group.