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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Alcohol Clin Exp Res. 2021 May 11;45(6):1188–1199. doi: 10.1111/acer.14619

Figure 3. Alcohol feeding is associated with impaired ileal FXR target gene expression and reduced hepatic CYP7A1 gene expression.

Figure 3.

Male C57BL/6J mice were fed control diet (CD) or alcohol diet (ED) and treated with vehicle (Veh) or GSK672 (4 mg/kg/day) as described in the “Materials and Methods”. A. Ileal mRNA expression. A ~1 cm segment of the distal ileum was used for mRNA expression measurement by real-time PCR. B. Liver mRNA expression. All results are expressed as mean±SEM (n=5-6). “*”, vs. CD+Veh. “#”, vs. ED+Veh.