. Author manuscript; available in PMC: 2022 Apr 1.

Published in final edited form as: J Magn Reson Imaging. 2020 Nov 12;53(4):1237–1250. doi: 10.1002/jmri.27437

TABLE 1.

Comparison of Metabolite’s Signal and CRLB Between Spiral-Out (SO) and Spiral-Out-In (SOI) in Phantom and Human Subjects

		tNAA	tCr	tCho	CRLB_NAA	CRLB_Cr	CRLB_Cho
Phantom	SO	5.87 ± 7.77	3.66 ± 3.61	8.40 ± 3.42	9.87 ± 4.50	11.12 ± 4.50	9.32 ± 5.40
	SOI	8.21 ± 3.83	5.43 ± 2.44	9.72 ± 4.29	7.07 ± 2.21	6.80 ± 2.30	5.93 ± 2.95
		P = 0.009	P = 0.0001	P = 0.01	P = 0.01	P = 0.02	P = 0.0001
Volunteers (n = 5)	SO	5.52 ± 6.60	3.15 ± 4.45	1.03 ± 3.37	8.14 ± 12.28	11.09 ± 13.81	10.51 ± 14.12
	SOI	6.52 ± 6.54	3.50 ± 4.44	1.05 ± 2.78	5.97 ± 10.09	7.40 ± 10.84	8.13 ± 12.02
		P = 0.0001	P = 0.003	P = 0.76	P = 0.02	P = 0.03	P = 0.04

Mean ± standard deviation of metabolite signals (a.u.) estimated by LCModel and the goodness of fit measure by Cramer–Rao lower bounds (CRLB) (%) of tNAA, tCr, and tCho.