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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Am J Med Genet A. 2021 Jul 30;185(12):3717–3727. doi: 10.1002/ajmg.a.62437

Table 1.

Association between UPSIT total score and participant characteristics

Characteristic N UPSIT Score Univariate P-value
Mean ± SD
All 127 35 ± 3 NA
Clinical Diagnosis 0.55
 USH2 80 35 ± 3
 ARRP 47 34 ± 4
Age at Enrollment (yrs) 0.90
 <30 30 34 ± 4
 30–39 34 34 ± 3
 40–49 37 35 ± 3
 50–59 11 34 ± 5
 ≥60 15 35 ± 3
Gender 0.34
 Female 68 35 ± 4
 Male 59 34 ± 3
Race/Ethnicity 0.63
 Non-Hispanic White 113 34 ± 3
 Other 14 35 ± 3
Duration of Disease (yrs) 0.38
 <10 37 34 ± 4
 10–19 46 34 ± 4
 ≥20 43 35 ± 3
Daily Smoker Ever 0.23
 Yes 33 34 ± 3
 No 94 35 ± 3
Country 0.02§
 Canada 4 38 ± 1
 France 13 34 ± 5
 Germany 11 36 ± 2
 Netherlands 10 32 ± 3
 UK 10 33 ± 3
 US 79 35 ± 3

Variable was analyzed as continuous.

One participant was missing age of onset (a participant-reported field based on their awareness of visual symptoms) and duration of disease (computed based on age of onset and date of enrollment)

§

Four participants from Canada were excluded from analysis due to small sample size.