Skip to main content
. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Am J Med Genet A. 2021 Jul 30;185(12):3717–3727. doi: 10.1002/ajmg.a.62437

Table 2.

Spearman correlation between UPSIT total score and visual function and structure measures

Visual Function Measures Correlation with UPSIT Score (95% C.I.) P-value
Visual Acuity −0.05 (−0.22, +0.13) 0.57
Full-field Stimulus Threshold
 White Stimulus +0.07 (−0.13, +0.27) 0.49
 Blue Stimulus +0.06 (−0.14, +0.27) 0.55
 Red Stimulus +0.11 (−0.09, +0.31) 0.28
Full-field Electroretinography
 DA 0.01 ERG Response −0.11 (−0.28, +0.07) 0.21
 DA 3.0 ERG Response§ −0.14 (−0.30, +0.04) 0.13
 LA 3.0 Flicker ERG Response −0.12 (−0.29, +0.06) 0.19
Kinetic Perimetry
 I4e Seeing Area −0.08 (−0.25, +0.10) 0.37
 III4e Seeing Area −0.09 (−0.26, +0.08) 0.30
 V4e Seeing Area −0.12 (−0.29, +0.06) 0.20
Ellipsoid Zone Area on Optical Coherent Tomography −0.10 (−0.27, +0.08) 0.26
Static Perimetry
 Full-field Hill of Vision −0.11 (−0.28, +0.07) 0.23
 30 Degree Hill of Vision −0.11 (−0.29, +0.07) 0.21
 Mean Sensitivity −0.10 (−0.27, +0.08) 0.26
Microperimetry Mean Retinal Sensitivity −0.11 (−0.31, +0.10) 0.32

Spearman partial correlation adjusted for age at enrollment.

The amplitude of the b-wave from the dark adapted 0.01 ERG response which reflects a rod-driven bipolar cell response.

§

The amplitude of the b-wave of the dark adapted 3.0 ERG response, which arises from a combined response of both rod and cone systems.

The trough-to-peak amplitude of the light-adapted 30 Hz flicker ERG response, which is cone-driven.