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. 2021 Dec 16;12:744532. doi: 10.3389/fphar.2021.744532

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Copyright © 2021 Aartsma-Rus, Dooms and Le Cam.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Share of reimbursed OMPs in selected EU Member States, by type of disease. Note: Between January 1995 and May 2000. Source: Copenhagen Economics based on historical average success rates from EMA data (European Medicines Agency 2020). Download medicine data. https://www.ema.europa.eu/en/medicines/download-medicine-data [Accessed april 21, 2021]).