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. 2021 Dec 16;12:744532. doi: 10.3389/fphar.2021.744532

FIGURE 4.

FIGURE 4

Which areas are concerned by a lack of authorised treatments? Note: 1) Based on authorisations between 2000 and 2017. 2) Based on orphan designations between 2000 and 2019. Source: 1) European Commission (2020, 40). 2) European Medicines Agency (2020, 6). 3) European Medicines Agency (2020, 5). 4) European Medicines Agency (2020, 13–14) and Wakap et al., 2020).