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. 2021 Dec 16;8:747629. doi: 10.3389/fmolb.2021.747629

FIGURE 8.

FIGURE 8

Pathway activity analysis of five prognostic core clock genes in pan-RCC. (A, B) The main role of five prognosis core clock genes in tumor-related marker pathways. Here, columns represent tumor-related marker pathways and rows represent genes, red represents rhythm genes activating immune-related pathways, and blue represents rhythm genes suppressing immune-related pathways. (C) Links between five prognosis core clock genes and hallmark signaling pathways. Solid lines represent rhythmic gene-activated immune-related pathways, and dashed lines represent immune-related pathways of rhythmic genes.