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. 2021 Oct 11;12(6):2101–2110. doi: 10.1002/jcsm.12817

Table 3.

Metabolome differences between cachectic patients with weight loss (WL) vs. stable weight (WS)

Estimated mean value WS/WL a 95% CI of mean value diff. P‐value q‐Value
Alanine DBS 0.379/−0.715 0.163–2.02 0.0252 0.3688
Alanine Plasma 0.378/−0.562 0.173–1.71 0.0204 0.5137
Tryptophan Plasma 0.593/−0.625 0.0819–2.36 0.0378 0.5137
3‐Methylglutaylcarnitine Plasma 0.921/−0.438 0.00536–2.71 0.0493 0.5137
Ornithine Plasma 1.44/0.607 0.0488–1.63 0.0392 0.5137
C16OH Plasma 0.0485/1.05 −1.91 to −0.0897 0.0347 0.5137
C18 Plasma 0.933/−0.675 0.0683–3.15 0.0430 0.5137
C201 DBS −0.924/0.479 −2.32 to −0.49 0.0064 0.1559
C6DC Plasma 0.922/−0.453 0.0286–2.72 0.0461 0.5137
Q14 DBS −1.06/0.288 −2.27 to −0.417 0.0097 0.1767
Q2 DBS −0.404/1.37 −2.66 to −0.879 0.0013 0.0459
Q3 DBS −0.0879/1.6 −2.45 to −0.919 0.0007 0.0459

Results are given according to binary categorization of weight loss from baseline (TP1) to the second (TP2) scheduled evaluation (Welch's two‐sided t‐test), n = 14. Only results with P‐value < 0.05 are reported. q‐Values represent results following correction for multiple testing.

95% CI, 95% C.I., 95% confidence interval; diff., difference; WL, weight loss; WS, weight stable.

a

Values represent SD.