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. 2021 Sep 28;12(6):1553–1569. doi: 10.1002/jcsm.12798

Figure 7.

Figure 7

Tauroursodeoxycholic acid (TUDCA) ameliorated the cancer cachexia symptoms of the cancer cachexia mice with inoculation of C26 tumour cells. (A) Body weight of different groups of mice. (B) Tumour‐free body weight of different groups of mice. (C) Accumulative food intake of different groups of mice. (D) Tumour growth curve of C26 tumour‐bearing mice with or without TUDCA treatment. (E) GA muscle tissue weight of different groups of mice. (F) eWAT fat tissue weight of different groups of mice. (G) Heart weight of different groups of mice. (H) Liver weight of different groups of mice. Data presented are the mean ± SEM of results of 10 mice in each group. TUDCA (50 mg/kg) was i.g. administrated daily. Ordinary one‐way analysis of variance for multiple comparisons was used to assess the significance of the difference. *P < 0.05; **P < 0.01, ***P < 0.001 indicate the significance between the indicated two groups (*vs. control group mice; #vs. cachexia group mice.).