Figure 3.

Effects of sciatic nerve dissection on collagen protein turnover in gastrocnemius muscle as compared with two types of control: sham leg in unilateral model of denervation (A–G) and non‐surgical control (H–K). Collagen accumulation in denervated muscle showed with picrosirius red staining (A–C). Collagen content in muscle measured by hydroxyproline assay (D,H). Collagen turnover calculated by steady‐state FSR (E,I) and non‐steady‐state (F,G,J,K) approaches. FSR, fractional synthesis rate; k _syn , synthesis rate; k _deg , Degradation rate; COL, collagen fraction.