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. 2021 Aug 25;12(6):1741–1756. doi: 10.1002/jcsm.12770

Figure 8.

Figure 8

Pim1 inhibition or knockout reduced the adipogenic differentiation of senescent PDGFRα+ mesenchymal progenitors by inhibiting the C/EBPδ pathway. (A) Detection of PPARγ, C/EBPβ, C/EBPδ, and FABP4 expression in PDGFRα+ mesenchymal progenitors through western blotting; GAPDH: internal reference. (B–E) Relative protein‐expression levels of PPARγ, C/EBPβ, C/EBPδ, and FABP4. (F) Detection of PPARγ, C/EBPβ, C/EBPδ, and FABP4 expression in murine gastrocnemius muscles through western blotting; GAPDH: internal reference. (G–J) Relative protein‐expression levels of PPARγ, C/EBPβ, C/EBPδ, and FABP4. N = 4–8; *P < 0.05, **P < 0.01, ***P < 0.001.