Table 2.
Baseline characteristics of cirrhotic patients in Cohort 2
| Group | Male(n = 296) | Female (n = 184) | P value |
|---|---|---|---|
| Age (years) (mean ± SD) | 51.93 ± 11.27 | 58.45 ± 12.08 | <0.001 |
| Height (m) (mean ± SD | 171.01 ± 4.95 | 160.02 ± 5.05 | <0.001 |
| Weight (kg) (mean ± SD) | 69.32 ± 10.41 | 59.15 ± 10.39 | <0.001 |
| Body mass index (kg/m2) | 23.68 ± 3.27 | 23.08 ± 3.86 | 0.089 |
| Aetiology | 0.031 | ||
| HBV (%) | 149 (50.34) | 59 (32.07) | |
| Alcohol (%) | 60 (20.27) | 1 (0.54) | |
| Autoimmune (%) | 1 (0.34) | 38 (20.65) | |
| Budd–Chiari (%) | 6 (2.03) | 6 (3.26) | |
| HCV (%) | 4 (1.35) | 1 (0.54) | |
| Schistosomiasis (%) | 5 (1.69) | 7 (3.80) | |
| Others (%) | 49 (16.55) | 71 (38.59) | |
| Combined (%) | 22 (7.43) | 1 (0.54) | |
| Serum indexes | |||
| RBC (1012/L) | 3.54 ± 0.82 | 3.41 ± 0.68 | 0.059 |
| WBC (109/L) | 4.44 ± 2.89 | 4.76 ± 7.63 | 0.516 |
| Haemoglobin (g/L) | 104.21 ± 29.86 | 97.80 ± 22.76 | 0.013 |
| Neutrophil (109/L) | 2.74 ± 2.34 | 3.64 ± 12.66 | 0.235 |
| PLT (109/L) | 109.04 ± 138.34 | 124.95 ± 153.93 | 0.241 |
| HCT (%) | 31.35 ± 7.91 | 29.71 ± 6.42 | 0.018 |
| TBil (μmol/L) | 34.99 ± 36.28 | 33.70 ± 42.84 | 0.724 |
| DBil (μmol/L) | 15.24 ± 27.20 | 14.17 ± 29.05 | 0.685 |
| Albumin (g/L) | 32.81 ± 6.11 | 32.32 ± 5.75 | 0.379 |
| ALT (U/L) | 45.60 ± 110.05 | 29.10 ± 22.39 | 0.045 |
| AST (U/L) | 52.97 ± 96.53 | 44.96 ± 34.35 | 0.280 |
| GGT (U/L) | 82.66 ± 144.63 | 59.93 ± 74.00 | 0.049 |
| Scr (μmol/L) | 73.83 ± 50.23 | 56.92 ± 25.31 | <0.001 |
| PT (s) | 16.08 ± 3.31 | 15.52 ± 2.92 | 0.061 |
| INR | 1.36 ± 0.34 | 1.31 ± 0.25 | 0.093 |
| K+ (mmol/L) | 3.90 ± 0.72 | 3.92 ± 2.31 | 0.892 |
| Na+ (mmol/L) | 136.52 ± 20.07 | 138.26 ± 15.11 | 0.310 |
| Cl− (mmol/L) | 103.26 ± 15.54 | 104.29 ± 11.83 | 0.442 |
| Child–Pugh score | 7.50 ± 2.14 | 7.45 ± 2.0 | 0.789 |
| Child–Pugh (%) | 0.410 | ||
| A | 112 (37.84) | 70 (38.04) | |
| B | 129 (43.58) | 88 (47.83) | |
| C | 55 (18.58) | 26 (14.13) | |
| MELD score | 11.75 ± 4.36 | 11.82 ± 3.60 | 0.851 |
| Complications | |||
| Ascites (%) | 189 (63.85) | 120 (65.22) | 0.755 |
| HE (%) | 26 (8.78) | 20 (10.87) | 0.451 |
| SBP (%) | 12 (4.54) | 9 (4.89) | 0.664 |
| UGIB (%) | 170 (57.43) | 102 (55.43) | 0.668 |
| AKI/HRS (%) | 6 (2.03) | 2 (1.09) | 0.435 |
| PVT (%) | 84 (28.38) | 48 (26.09) | 0.586 |
AKI, acute kidney injury; ALT, glutamic‐pyruvic transaminase; AST, glutamic‐oxalacetic transaminase; DBil, direct bilirubin; GGT, gamma‐glutamyl transferase; HCT, hematocrit; HE, hepatic encephalopathy; HRS, hepatorenal syndrome; TBil: total bilirubin; INR, international normalized ratio; MELD, model for end‐stage liver disease; PLT, blood platelet; PT, prothrombin time; PVT, portal venous thrombosis; RBC, red blood cell; SBP, spontaneous bacterial peritonitis; UGIB, upper gastrointestinal bleeding; WBC, white blood cell.