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. 2021 Dec 30;100(52):e27411. doi: 10.1097/MD.0000000000027411

Figure 6.

Figure 6

The risk of DAPT-related upper GI bleeding in patients receiving any PPI versus those without PPI. The risk of MACE with half-dose PPI co-therapy was also superior to that in the histamine 2 receptor antagonist (H2RA) treatment groups. The high-dose cutoff points were esomeprazole > 40 mg, omeprazole > 20 mg, pantoprazole > 40 mg, rabeprazole > 20 mg, and lansoprazole > 30 mg. CI = confidence interval, DAPT = dual antiplatelet therapy, GI = gastrointestinal, MACE = major adverse cardiac events, PPI = proton pump inhibitor.