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. 2021 Nov 29;40(2):171–179. doi: 10.1200/JCO.21.02014

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FIG 2. — (A) Kaplan-Meier OS curves for patients with metastatic LCC that bore GOF versus non-GOF mutp53. Median OS was 24.6 (GOF, n = 139) versus 33.5 (non-GOF, n = 381) months, P = .01. (B) Kaplan-Meier OS curves for patients with metastatic RCC with GOF versus non-GOF p53 mutp53. Median OS was 23.6 (RCC mutp53 GOF, n = 65) versus 13.8 (RCC mutp53 non-GOF, n = 150) months, P = .08. GOF, gain-of-function; LCC, left-sided colorectal cancer; mutp53, p53 mutation; non-GOF, non–gain-of-function; OS, overall survival; RCC, right-sided colon cancer.