Table 2.
Long-term change in clinical parameters.
| P | |||||||||
| Outcome | Groups | Baseline [1] | 4 weeks [2] | 8 weeks [3] | 12 weeks [4] | 24 weeks [5] | Time | Group | Time × Group |
| Pain intensity (NRS)† | Intervention | 3.8 (2.4) | 2.1 (1.8) | 1.8 (1.8) | 1.4 (1.5) | 0.9 (1.1) | <.001∗∗ | .026∗ | .786 |
| Control | 4.6 (2.0) | 2.8 (1.9) | 2.3 (1.7) | 2.0 (1.6) | 1.6 (1.7) | ||||
| Comfortable mouth opening (mm)† | Intervention | 35.6 (10.9) | 42.2 (9.0) | 42.7 (9.3) | 43.7 (8.5) | 44.3 (8.7) | <.001∗∗ | .986 | .398 |
| Control | 38.1 (8.8) | 42.7 (7.9) | 42.7 (7.7) | 42.9 (7.8) | 43.3 (7.7) | ||||
| Maximum mouth opening (mm)† | Intervention | 43.3 (8.4) | 45.3 (10.0) | 45.0 (7.1) | 45.8 (7.2) | 46.0 (7.3) | .001∗∗ | .920 | .772 |
| Control | 43.0 (8.1) | 44.8 (6.9) | 45.6 (6.0) | 45.6 (5.8) | 45.6 (6.2) | ||||
| Pain on palpation: capsule‡ | Intervention | 17/45 (38%) | 15/45 (33%) | 13/45 (29%) | 5/45 (11%) | 5/45 (11%) | <.001∗∗ | .386 | .138 |
| Control | 16/41 (39%) | 16/41 (39%) | 8/41 (20%) | 9/41 (22%) | 10/41 (24%) | ||||
| Pain on palpation: muscle‡ | Intervention | 26/45 (58%) | 18/45 (40%) | 18/45 (40%) | 16/45 (36%) | 14/45 (31%) | <.001∗∗ | .168 | .857 |
| Control | 28/41 (68%) | 23/41 (56%) | 20/41 (49%) | 20/41 (49%) | 18/41 (44%) | ||||
| Noise‡ | Intervention | 33/45 (72%) | 28/45 (62%) | 23/45 (51%) | 25/45 (56%) | 24/45 (53%) | .567 | .645 | .018∗ |
| Control | 23/41 (56%) | 27/41 (66%) | 28/41 (68%) | 26/41 (63%) | 26/41 (63%) | ||||