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. Author manuscript; available in PMC: 2021 Dec 30.
Published in final edited form as: J Proteome Res. 2016 Jul 8;15(8):2455–2465. doi: 10.1021/acs.jproteome.5b01129

Figure 1.

Figure 1.

Protein expression levels were associated with platinum response of ovarian serous carcinoma patients. (A) Patients with similar platinum responses shared certain proteomic signatures. In this heatmap, each row is a patient, and each column is a protein. Hierarchical clustering results showed that platinum-resistant patients formed clusters, indicating that these protein signatures are correlated with platinum status of ovarian serous carcinoma patients. (B) Log expression levels of proteins associated with platinum response status. Abundance levels of 24 proteins, including KRT19, KRT4, ACTN4, RANBP1, IGLL5, and TPMT, were strongly associated with the clinical platinum response in ovarian serous carcinoma patients.