Figure 1.

Spectral domain optical coherence tomography (SD-OCT) drusen segmentation example in different views. 3D surface view with the estimation of Bruch’s membrane surface indicated in green and the detected drusen regions identified in magenta (volumetric properties). Topographic view of a drusen elevation map with individual drusen indicated in magenta (area, extent, and density properties). The dotted green and yellow lines indicate B-scan locations. B-scan view, with generated druse outlines shown in magenta. The blue square identifies a region shown in detail, where indications of drusen height, slope and reflectivity are shown. Adapted from: Hallak JA, de Sisternes L, Osborne A, Yaspan B, Rubin DL, Leng T. Imaging, genetic, and demographic factors associated with conversion to neovascular age-related macular degeneration: secondary analysis of a randomized clinical trial. JAMA Ophthalmol 2019;137:738–44. (A color version of this figure is available in the online journal.)