Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Dec 25;9(12):e003973. doi: 10.1136/jitc-2021-003973

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

(A) Violin plots show the gene expression level of each sample, the width of each violin represents the number of genes under this expression level. (B) Hierarchical clustering of the differentially expressed genes associated with EMT in the OvCa cells and OvCa cells isolated from spheroids (p<0.05). Each group contains three samples. (C) GO classification of differential expressed genes in comparisons between OvCa cells and OvCa isolated from spheroids. The ordinate is the number of differentially expressed genes and the abscissa represents the GO term name. Orange represented biological process, blue represented cellular component and green represented molecular function. (D) KEGG pathway analysis revealed the enrichment of several important pathways among the differential expressed genes, including transcriptional misregulation in cancer and focal adhesion. EMT, epithelial-mesenchymal transition; GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; OvCa, ovarian cancer; TNF, tumor necrosis factor.