Table 4.
Multivariable linear regression for factors related to tissue characteristics.
| Multivariable | |||
|---|---|---|---|
| β-estimate | 95% confidence interval | p-value | |
| Native T1 (ms) | |||
| Ischemia (% of LV)* | 9.018 | 4.721; 13.315 | <0.001 |
| MWT (mm) | 2.569 | 0.981; 4.157 | 0.002 |
| ECV (%) | |||
| Ischemia (% of LV)* | 0.002 | −0.005; 0.009 | 0.566 |
| MWT (mm) | 0.003 | 0.001; 0.005 | 0.016 |
| LGE (%of LV) | |||
| Ischemia (% of LV)* | 1.070 | −0.106; 2.245 | 0.074 |
| MWT (mm) | 0.716 | 0.276; 1.155 | 0.002 |
| Subgroup analysis | |||
| MWT 15–20 mm | |||
| Ischemia (% of LV)* | 1.941 | 0.738; 3.143 | 0.002 |
| LV mass (g/m2) | 0.122 | 0.012; 0.231 | 0.031 |
| MWT ≥21mm | |||
| Ischemia (% of LV)* | 0.050 | −2.213; 2.314 | 0.964 |
| Nonobstructive HCM | |||
| Ischemia (% of LV)* | 1.471 | 0.258; 2.683 | 0.019 |
| MWT (mm) | 0.553 | 0.068; 1.038 | 0.026 |
| Obstructive HCM | |||
| Ischemia (% of LV)* | −1.073 | −4.161; 2.015 | 0.476 |
| MWT (mm) | 1.284 | 0.307; 2.262 | 0.013 |
| Male | |||
| Ischemia (% of LV)* | 0.436 | −1.287; 2.159 | 0.613 |
| MWT (mm) | 0.939 | 0.312; 1.566 | 0.004 |
| Female | |||
| Ischemia (% of LV)* | 1.957 | 0.423; 3.492 | 0.015 |
| Age <40years | |||
| Ischemia (% of LV)* | 4.874 | 1.155; 8.594 | 0.016 |
| MWT (mm) | 1.380 | 0.608; 2.153 | 0.003 |
| Age ≥40 years | |||
| Ischemia (% of LV)* | 1.145 | −0.141; 2.431 | 0.080 |
| MWT (mm) | 0.515 | −0.004; 1.034 | 0.052 |
| T2(ms) | |||
| Ischemia (% of LV)* | 0.280 | −0.010; 0.580 | 0.061 |
| Non-obstructive HCM | −1.294 | −2.389; −0.199 | 0.021 |
ECV, extracellular volume; HCM, hypertrophic cardiomyopathy; LGE, late gadolinium enhancement; LV, left ventricle; MWT, maximum wall thickness.
*
For each 10% increment of ischemia.