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. 2021 Dec 17;12:755356. doi: 10.3389/fneur.2021.755356

Figure 6.

Figure 6

Association between the anti-AChR Ab levels and the ratios of Treg subgroups in MG patients. Shapiro-Wilk's tests were used to assess normal distribution of the data. We identified one outlier using outlier boxplot tool, and this outlier was omitted from graphical presentation of the data, with no effects on the statistical results. Linear regressions (solid black lines) with 95% CI (dotted lines) were conducted to analyze the relationship between the anti-AChR Ab levels and the ratios of Treg subgroups in MG patients, and slopes were compared to 0 in addition to Spearman's correlation test in order to access correlations between variables. (A), no significant correlation between anti-AChR Ab concentration and FoxP3+ Treg/CD4+T ratio. (B), a positive correlation with statistically significant was found between Tr1/CD4+T cell ratio and the level of anti-AChR Ab (r = 0.6889 ± 0.4414, p = 0.0401). (C), a positive correlation with statistically significant was discovered between Tr1/FoxP3+ Tregs cell ratio and the level of anti-AChR Ab (r = 0.7110 ± 0.4227, p = 0.0318). N = 9 for MG patients (one outlier was omitted).