TABLE 4.
Commercial applications of bioactive natural products with endophytic fungi (EFs)-based biogenesis.
Application fields | Reported products | Endophytic fungal sources | References |
Pharmaceuticals | Taxol (anticarcinogenic agent) | Paraconiothyrium SSM001 | Soliman et al., 2013 |
Cycloepoxytriol B (antibiotic agent) | Phomopsis sp. | Hussain et al., 2009 | |
Flavor and fragrance | Methyl eugenol [1,2-dimethoxy 4-(2-propenyl) benzene] | Alternaria sp. | Kaul et al., 2008 |
Cosmetics (cream, shampoos, lotions, toothpaste, etc.) | Fatty acids (e.g., oleic, stearic, linoleic, and palmitic acid) | Bionectria ochroleuca, C. truncatum, Chaetomium sp. | George et al., 2011; Kumar and Kaushik, 2013; Yang Y. et al., 2015 |
Chitosan | A. flavus, C. cladosporioides, Phoma sp. | George et al., 2011 | |
Food industry | Chitosan (as food additive) | A. flavus, C. cladosporioides, Phoma sp. | Liu et al., 2008; George et al., 2011 |
7-amino-4-methylcoumarin (food preservative agent) | Xylaria sp. | Liu et al., 2008 | |
Bioinsecticides | Loline alkaloids | N. uncinatum | Aly et al., 2010 |
Bioherbicides | Ascotoxin (growth inhibitory effect) | Paraconiothyrium sp. | Khan et al., 2012 |
Nutraceuticals | Saponins | Aspergillus, Bulgaria, Penicillium, Phomopsis sp. | Nicoletti and Fiorentino, 2015 |