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. 2021 Dec 17;8:782151. doi: 10.3389/fmed.2021.782151

Table 5.

Subgroup analysis of need for rescue analgesia.

Outcomes of interest No. of patients Effect estimate Heterogeneity
No. of studies Experimental Control WMD/OR (95% CI) P -value I2 (%) P -value
Analgesics vs. Controls
NSAIDs vs. Controls 2 109 109 0.25 (0.06, 0.99) 0.05 45 0.18
Opioids vs. Non-opioids
Opioids vs. NSAIDs 4 83 84 0.56 (0.24, 1.32) 0.18 0 0.90
Opioids vs. Local anaesthetics 2 70 71 0.02 (0.00, 0.08) <0.00001 0 0.81

WMD, weighted mean difference; OR, odds ratio; CI, confidence interval; NSAID, non-steroidal anti-inflammatory drug.