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. 2021 Dec 17;12:779195. doi: 10.3389/fgene.2021.779195

FIGURE 2.

FIGURE 2

Hsa-circRNA_0001400_siRNA promotes the apoptosis of cervical cancer cells and causes G1-phase arrest of the cell cycle. (A) hsa_circRNA_0001400 in human vaginal epithelial, cervical cancer SiHa, and HeLa cell lines. (B) The effect of hsa_circRNA_0001400_siRNA on the apoptosis of cervical cancer cells. (C) The effect of hsa_circRNA_0001400_siRNA on the cell cycle of cervical cancer cells. (D) The effect of hsa_circRNA_0001400_siRNA on cervical cancer colony formation. (E) The effects of hsa_circRNA_0001400_siRNA on Akt, Phospho-Akt (Ser473), PI3K, and Phospho-PI3 Kinase p85 (Tyr458) protein expression in cervical cancer cells. Data are expressed as mean ± standard deviation, n = 3, *p < 0.05 and * *p < 0.01 vs. control group.