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. 2021 Dec 17;12:779195. doi: 10.3389/fgene.2021.779195

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Copyright © 2021 Cai, Li, Peng, Yin, Liang, Su, Li, Yang, Liu, Yang, Luo and Xia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Direct interaction of hsa-circRNA_0001400, miR-326, and Akt. (A) Bioinformatics prediction of the direct interaction sites of hsa_circRNA_0001400 and miR-326. (B) Bioinformatics prediction of the direct interaction of miR-326 and Akt. (C) The direct interaction between hsa_circRNA_0001400 and miR-326 was analyzed by double luciferase reporter gene analysis. (D) The direct interaction between miR-326 and Akt was analyzed by double luciferase reporter gene analysis. Data are expressed as mean ± standard deviation, n = 3, *p < 0.05 and * *p < 0.01 vs. control group.