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. 2021 Dec 17;9:711149. doi: 10.3389/fcell.2021.711149

FIGURE 1.

FIGURE 1

ITGB1 was highly expressed in human LIHC. (A) mRNA expression of ITGB1 in normal tissues (n = 50) and LIHC tissues (n = 369) derived from TCGA data. (B) mRNA expression of ITGB1 in LIHC patients of stage I to IV derived from TCGA data. (C) ITGB1 mRNA level of LIHC tissues (n =10) was quantified by qRT-PCR and normalized to that of tumor-adjacent normal tissues (n = 10). Wilcoxon test was used to perform a statistical test. *p < 0.05, ***p < 0.001, ****p < 0.0001. (D) Representative images of ITGB1 immunohistochemical staining in paired tumor-adjacent normal tissues (n = 10) and LIHC tissues (n = 10). Scale bar = 50 µm. (E) ITGB1 protein level of LIHC tissues (n = 10) was quantified by immunohistochemical staining and normalized to that of tumor-adjacent normal tissues (n = 10). (F) Kaplan–Meier overall survival curve was shown according to high and low expression of ITGB1 in LIHC patients derived from TCGA data. Values are presented in mean ± SD. **p < 0.01.