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. 2021 Dec 10;27:304–318. doi: 10.1016/j.omtn.2021.12.003

Figure 5.

Figure 5

Combining the responses of endogenous reporters to identify potential NMD modulators

(A) Venn diagrams using a threshold of the NMD/non-NMD ratio above (the average + 3xSD). (B) Venn diagrams using a threshold of the NMD/non-NMD ratio above (the average + 2xSD). (C) Venn diagrams using a threshold of the NMD/non-NMD ratio above (the average +1.5xSD). (D) Venn diagrams using a threshold of the NMD/non-NMD ratio below (the average −1.5xSD). (E) Fisher tests obtained 9 inhibitors and 1 enhancer with a threshold of FDR_Fisher ≤0.01. (F) Randomization tests obtained 3 inhibitors and 3 enhancers with FDR_ permutation ≤0.01.