Table 3.
DXA scan results at age 6 years by combination of vitamin D status and prenatal high-dose vitamin D supplementation.
| COPSAC2010 | Combined: Prenatal supplementation and 6 year vitamin D status |
||
|---|---|---|---|
| Age 6y DXA | High-dose and sufficient (n = 47) vs. Standard-dose and insufficient (n = 120) aMD (95% CI) |
High-dose and insufficient (n = 110) vs. Standard-dose and insufficient (n = 120) aMD (95% CI) |
Standard-dose and sufficient (n = 41) vs. Standard-dose and insufficient (n = 120) aMD (95% CI) |
| Total BMD, g/cm2 | 0.016 (0.002;0.030) p = 0.03 | 0.009 (−0.002;0.019) p = 0.10 | 0.015 (0.0002;0.029) p = 0.047 |
| Total BMC, g | 23.5 (5.5;41.5) p = 0.01 | 13.8 (0.1;27.6) p = 0.049 | 13.9 (−5.0;32.7) p = 0.15 |
| TBLH BMD g/cm2 | 0.008 (−0.002;0.019) p = 0.13 | 0.005 (−0.004;0.013) p = 0.26 | 0.011 (−0.0002;0.022) p = 0.05 |
| TBLH BMC g | 11.0 (−1.1;23.1) p = 0.08 | 7.9 (−1.4;17.2) p = 0.10 | 8.0 (−4.7;20.7) p = 0.22 |
| Head BMD g/cm2 | 0.048 (0.009;0.086) p = 0.02 | 0.035 (0.005;0.064) p = 0.02 | 0.038 (−0.003;0.078) p = 0.07 |
| Head BMC g | 12.5 (3.0;22.0) p = 0.01 | 6.0 (−1.3;13.2) p = 0.11 | 6.0 (−4.0;15.9) p = 0.24 |
aMD: Adjusted mean difference for age, sex, height and weight.