Figure 1.

Summarized methods of detection, the qualitative/quantitative IFN-γ specific binding, and functional assays of anti-IFN-γ AAbs. IFN-γ: interferon gamma; AAbs: autoantibodies; ELISA: enzyme-linked immunosorbent assay; QFT-GIT: QuantiFERON-TB gold in-tube; LIPS: luciferase immunoprecipitation system; STAT1: signal transducer and activator of transcription 1; PBMC: peripheral blood mononuclear cell; TNF: tumor necrosis factor; IL: interleukin; MHC: major histocompatibility complex. (A color version of this figure is available in the online journal.)