. 2021 Dec 16;12:785085. doi: 10.3389/fmicb.2021.785085

TABLE 1.

Overview of the gene-encoded AMPs from marine invertebrates, including some key features.

Phyla	AMP types	Origin	Size	Cys	Activity spectrum^a
Annelida	Arenicins	Coelomocytes	21 aa	2	G⁺, G^–, F
	Perinerin	Homogenate	51 aa	4	G⁺, G^–, F
	Hedistin	Coelomocytes	22 aa	0	G⁺, G^–, F
Mollusca	Defensin	Hemocytes	39–43 aa	6–8	G⁺, G^–
	Mytilin	Hemocytes	32–34 aa	8	G⁺, G^–, F
	Myticin	Hemocytes	40 aa	8	G⁺, (G^–, F)
	Mytimycin	Hemocytes	54 aa	12	F
Arthropoda	Tachyplesins	Hemocytes	17 aa	4	G⁺, G^–, F
	Polyphemusins	Hemocytes	18 aa	4	G⁺, G^–, F
	Penaeidins	Hemocytes	47–67 aa	6	G⁺, (G^–), F
Cnidaria	Aurelin	Ectoplasm	40 aa	6	G⁺, G^–b
Tunicata	Styelins	Hemocytes	31–32 aa	0	G⁺, G^–b
	Clavanins	Hemocytes	23 aa	0	G⁺, G^–, F
	Clavaspirin	Pharyngeal	23 aa	0	G⁺, G^–, F
	Plicatamide	Hemocytes	26 aa	0	G⁺, G^–b
	Halocyamine	Hemocytes	4 aa	0	G⁺, G^–, F
	Dicynthaurin^c	Hemocytes	30 aa	2	G⁺, G^–
	Halocidin^c	Hemocytes	18 aa	2	G⁺, G^–, F^d

^aG⁺, Gram-positive bacteria; G^–, Gram-negative bacteria; F, fungi. Brackets indicate microorganisms with considerably lower susceptibility to the AMP.

^bThe AMP has not been screened against all groups of microorganisms included in this table.

^cDimeric AMPs.

^dA synthetic analog of halocidin showed antifungal activity.