TABLE 1.
Characteristics of the eligible studies.
| Author, year | Country | Population | Participant s age (years) | Sample size: tibolone/placebo | Duration | Baseline BMI(kg/m2) | Outcome | Vitamin D dose (IU/day) |
|---|---|---|---|---|---|---|---|---|
| Kerksick.et al. (2020) (a) (CTL = no diet + exercise control) | USA | Healthy postmenopausal women | 56.1 | 11/9 | 14 weeks | 31.8 | LDL-C, TC, HDL-C, TG | 400 (calcium with Vitamin D) |
| Kerksick.et al. (2020) (b) (LCHC = low calorie high carbohydrate diet) | USA | Healthy postmenopausal women | 54.4 | 15/20 | 14 weeks | 32.6 | LDL-C, TC, HDL-C, TG | 400 (calcium with Vitamin D) |
| Kerksick.et al. (2020) (c) (LCHP = low calorie high protein diet) | USA | Healthy postmenopausal women | 52.4 | 16/18 | 14 weeks | 36.4 | LDL-C, TC, HDL-C, TG | 400 (calcium with Vitamin D) |
| Ferreira et al. (2020) | Brazil | Healthy postmenopausal women | 58.8 | 80/69 | 9 months | 29.4 | LDL-C, TC, HDL-C, TG | 1000 |
| Bislev et al. (2018) | Denmark | Healthy postmenopausal | 65 | 40/41 | 12 weeks | 27 | LDL-C, HDL-C, TG | 2800 |
| Munoz-Aguirre et al. (2015) | Mexico | Healthy postmenopausal women | 43.55 | 52/52 | 6 months | 30.8 | LDL-C, TC, HDL-C, TG | 4000 |
| Moghassemi and Marjani. (2014) | Iran | Healthy postmenopausal women | 52.73 | 38/36 | 12 weeks | 29.98 | LDL-C, TC, HDL-C, TG | 2000 |
| Wood et al. (2012) (a) | United Kingdom | Healthy postmenopausal women | 63.5 | 97/50 | 1 year | 26.6 | LDL-C, TC, HDL-C, TG | 400 |
| Wood et al. (2012) (b) | United Kingdom | Healthy postmenopausal women | 64.1 | 95/50 | 1 year | 26.8 | LDL-C, TC, HDL-C, TG | 1000 |
| Heikkinen et al. (1997) (a) | Finland | Healthy postmenopausal women | 52.8 | 83/95 | 3 years | 26.8 | LDL-C, TC, HDL-C, TG | 300 |
| Heikkinen et al. (1997) (b) | Finland | Healthy postmenopausal women during postmenopausal hormone replacement therapy | 52.4 | 77/65 | 3 years | 26.4 | LDL-C, TC, HDL-C, TG | 300 |
Note: HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, serum triglycerides; mg/d, milligrams per day; USA, United States of America.