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. Author manuscript; available in PMC: 2021 Dec 31.
Published in final edited form as: Nat Struct Mol Biol. 2021 Nov 10;28(11):936–944. doi: 10.1038/s41594-021-00679-2

Fig. 6. Cryo-EM structure of the complex of isoproterenol-bound β1-AR and Gi/s.

Fig. 6

a–c, Cryo-EM density maps, in three views (a, b and c), of the β1-AR-Gi/s complex colored by subunit (β1-AR in red, Gαi/s Ras-like domain in green, Gαi/s α-helical domain in orange, Gβ in blue, Gγ in yellow). d, Comparison of the α5-helices in the β1-AR–Gi complex (gray) and the β1-AR–Gi/s complex (in dark teal with the last 11 amino acid residues from Gαsin violet) when β1-ARs are superimposed.