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. 2021 Dec 17;12:747638. doi: 10.3389/fphar.2021.747638

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Copyright © 2021 Natella, Guantario, Ambra, Ranaldi, Intorre, Burki and Canali.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Box plot representation of gallotannin metabolites in plasma (µg/ml) after Hamaforton™ and placebo capsule ingestion (time 0, time 1, time 3 and time 5 h). The red crosses correspond to the means, while the central horizontal bars represent the medians. The lower and upper limits of the box correspond to the first and third quartiles, respectively. Data were analysed through Kruskal-Wallis and Friedman test as opportune. *indicates significant differences compared to time 0 (p < 0.05).