TABLE 4.
Effect of 18KHT01 and its ingredients on fasting blood glucose level.
| Groups | Week 0 | Week 3 | Week 6 | Week 9 |
|---|---|---|---|---|
| Normal | 76.6 ± 8.6 | 60.0 ± 11.9 | 73.2 ± 3.8 | 80.6 ± 12.0 |
| HFD Control | 83.0 ± 14.0 | 102.4 ± 20.2## | 113.6 ± 17.6### | 115.4 ± 14.1### |
| 18KHT01 | 67.6 ± 7.7 | 89.2 ± 11.3# | 90.6 ± 9.3* | 79.2 ± 5.0*** |
| C. sinensis (CS) | 75.0 ± 10.5 | 98.2 ± 9.5## | 96.2 ± 13.0# | 89.0 ± 11.8** |
| Q. acutissima (QA) | 79.4 ± 22.3 | 106.8 ± 28.8### | 109.0 ± 11.3## | 104.0 ± 11.7# |
| G. thunbergii (GT) | 84.6 ± 21.5 | 124.0 ± 9.9 | 125.0 ± 17.0 | 117.0 ± 4.2 |
| Orlistat | 75.6 ± 19.0 | 87.4 ± 8.2# | 108.6 ± 13.8### | 104.0 ± 9.8# |
Blood glucose was measured in every 3 weeks interval in a fasting condition during in vivo synergy evaluation study. The results are expressed in mg/dL. Statistical significance was calculated using one-way ANOVA, followed by Dunnett’s multiple comparisons test. Values are presented as the mean ± SD (n = 5) with significance #p < 0.05, ##p < 0.01, ###p < 0.001 vs Normal; **p < 0.01, ***p < 0.001 vs HFD, group. Normal = standard diet; HFD, high-fat diet control; CS, Camellia sinensis (150 mg/kg); QA, Quercus acutissima (150 mg/kg); GT, Geranium thunbergii (150 mg/kg); Orlistat = orlistat (10 mg/kg).